Mechanisms of catalyses: opposing relationship with enzyme stability.
نویسنده
چکیده
Nakamura, S. & Hayashi, S. (1974) FEBSLett. 41,327-330 Pazur, J. H., Knull, H. R. and Simpson, D. L. (1970) Biochem. Biophys. Res. Commun. 40, 110-1 16 Ryle, M., Chaplin, M. F., Gray, C. J. & Kennedy, J. F. (1970) in Gonadotrophins and Ovarian Development (Butt, W. R., Crooke, A. C. & Ryle, M., eds.), pp. 98-106, Livingstone, Edinburgh 1081-1087 Samy, T. S. A. (1967) Arch Biochem. Biophys. 121,703-7 10 Schmid, K., Bencze, W. L., Nussbaumer, T. & Wehrmuller, J. 0. (1959) J. Biol. Chem. 234,529-533 Terminiello, L., Sri Ram, J., Bier, M. & Nord. F. F. (1955) Arch. Biochem. Biophys. 51,252-26 1 Torchilin, V. P., Mazaer, A. V., Il'ina, E. V., Goldmacher, V. S., Smirnov, V. M. & Chazov, E. I. (1980) Enzvme Engineering, Future Directions 2978 (Wingard, L. B., Berezin, 1. V. & Klyosov, A. A.. eds.), pp. 219-240, Plenum Press, New York Vegarud, G. & Christensen, T. B. (1975) Biotechnol. Bioeng. 17, 1391-1397
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عنوان ژورنال:
- Biochemical Society transactions
دوره 11 1 شماره
صفحات -
تاریخ انتشار 1983